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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 10-Q
Quarterly Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934
For the Quarterly Period Ended October 1, 2023
Transition Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934
For the transition period from             to            
Commission File Number 001-35406 
ilmnlogoa191.jpg
Illumina, Inc.
(Exact name of registrant as specified in its charter)
Delaware33-0804655
(State or other jurisdiction of incorporation or organization)(I.R.S. Employer Identification No.)
5200 Illumina Way, San Diego, CA 92122
(Address of principal executive offices) (Zip code)
(858) 202-4500
(Registrant’s telephone number, including area code)
N/A
(Former name, former address and former fiscal year, if changed since last report)
Securities registered pursuant to Section 12(b) of the Act:
Title of each classTrading Symbol(s)Name of each exchange on which registered
Common Stock, $0.01 par valueILMNThe Nasdaq Stock Market LLC
Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days.    Yes       No  
Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S-T during the preceding 12 months (or for such shorter period that the registrant was required to submit such files).    Yes       No  
Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, smaller reporting company, or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company,” and “emerging growth company” in Rule 12b-2 of the Exchange Act.
Large accelerated filerþAccelerated filer
Non-accelerated filer
Smaller reporting company
Emerging growth company
If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13a of the Exchange Act.     
Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act).     Yes      No   þ
As of November 6, 2023, there were 158.8 million shares of the registrant’s common stock outstanding.


ILLUMINA, INC.
FORM 10-Q
FOR THE FISCAL QUARTER ENDED OCTOBER 1, 2023
TABLE OF CONTENTS

See “Form 10-Q Cross-Reference Index” within Other Key Information for a cross-reference to the parts and items requirements of the Securities and Exchange Commission Quarterly Report on Form 10-Q.

CONDENSED CONSOLIDATED FINANCIAL STATEMENTSPAGE
MANAGEMENT’S DISCUSSION & ANALYSIS
OTHER KEY INFORMATION
2

Consideration Regarding Forward-Looking Statements
This Quarterly Report on Form 10-Q contains, and our officers and representatives may from time to time make, “forward-looking statements” within the meaning of the safe harbor provisions of the U.S. Private Securities Litigation Reform Act of 1995. Words such as: “anticipate,” “intend,” “plan,” “goal,” “seek,” “believe,” “continue,” “project,” “estimate,” “expect,” “strategy,” “future,” “likely,” “may,” “potential,” “predict,” “should,” “will,” or similar words or phrases, or the negatives of these words, may identify forward-looking statements, but the absence of these words does not necessarily mean that a statement is not forward looking. Examples of forward-looking statements include, among others, statements we make regarding:
our expectations as to our future financial performance, results of operations, or other operational results or metrics;
the benefits that we expect will result from our business activities and certain transactions we have completed, or may complete, such as product introductions, increased revenue, decreased expenses, and avoided expenses and expenditures;
our expectations of the effect on our financial condition of claims, litigation, contingent liabilities, and governmental investigations, proceedings, and regulations;
our strategies or expectations for product development, market position, financial results, and reserves;
our ability to successfully implement cost reduction plans in a timely manner and the possibility that costs associated with our cost reduction plans are greater than we anticipate;
our expectations regarding the outcome of the legal and regulatory proceedings, including appeals, related to our acquisition of GRAIL, Inc. (GRAIL) and other actions that may be taken or pursued by the European Commission, the U.S. Federal Trade Commission (FTC) and/or other governmental or regulatory authorities in connection with such acquisition;
the transitional measures imposed by the European Commission, the duration and impact of such measures on Illumina and GRAIL, and the appointment of a monitoring trustee to monitor our compliance with such measures;
the prohibition decision adopted by the European Commission on September 6, 2022 (the Prohibition Decision), informing us of its decision to prohibit our acquisition of GRAIL, and the decision adopted by the European Commission on October 12, 2023 requiring us to (among other things) divest GRAIL and imposing transitional measures (the EC Divestment Decision);
the opinion and order issued by the FTC on March 31, 2023 (the FTC Order), requiring us to divest GRAIL and to hold GRAIL separate through the completion of the divestiture;
the Article 14(2)(b) fine imposed by the European Commission on July 12, 2023; and
other expectations, beliefs, plans, strategies, anticipated developments, and other matters that are not historical facts.
Forward-looking statements are neither historical facts nor assurances of future performance. Instead, they are based only on our current beliefs, expectations, and assumptions regarding the future of our business, future plans and strategies, projections, anticipated events and trends, the economy, and other future conditions. Because forward-looking statements relate to the future, they are subject to inherent uncertainties, risks, and changes in circumstances that are difficult to predict and many of which are outside of our control. Our actual results and financial condition may differ materially from those indicated in the forward-looking statements. Therefore, you should not rely on any of these forward-looking statements. Important factors that could cause our actual results and financial condition to differ materially from those indicated in the forward-looking statements include, among others, the following:
our expectations and beliefs regarding prospects and growth for our business and the markets in which we operate;
the timing and mix of customer orders among our products and services;
3

challenges inherent in developing, manufacturing, and launching new products and services, including expanding manufacturing operations and reliance on third-party suppliers for critical components;
the impact of recently launched or pre-announced products and services on existing products and services;
risks and uncertainties regarding the legal and regulatory proceedings, including the failure to obtain or delays in obtaining the required regulatory approvals or clearances including for any potential divestiture of GRAIL, any appeals relating to our acquisition of GRAIL and our ability to achieve the expected benefits of such acquisition and other actions that have been or may be taken or pursued by the European Commission, the FTC and/or other governmental or regulatory authorities in connection with such acquisition;
the transitional measures and hold separate requirements imposed by the European Commission, the duration and impact of these requirements on Illumina and GRAIL (which may include material and adverse effects on benefits we expect to achieve as a result of the acquisition of GRAIL, additional costs or liabilities, loss of revenue and other adverse effects on our business, financial condition and results of operations) and the administration of these requirements by an appointed monitoring trustee;
our compliance with burdensome transitional measures imposed by the European Commission and the risk that the European Commission could impose or seek to impose additional fines and other penalties for alleged noncompliance with these requirements;
the EC Divestment Decision and the FTC Order, which may each adversely affect us and our business, including current plans and operations, financial condition and results of operations, each requiring us to divest GRAIL and to hold GRAIL separate through the completion of the divestiture, the terms and conditions thereof (including with respect to a divestiture of GRAIL), and the timing of and the risks, costs and business disruptions (including the diversion of management’s attention) associated with such divestiture and/or any related appeals, the implementation thereof or any associated legal or regulatory proceedings or obligations, including any related appeals, and other uncertainties related to our compliance (or ability to comply) with each of the EC Divestment Decision and the FTC Order, which may adversely affect us and our business, including current plans and operations, financial condition and results of operations;
risks associated with contracts or other agreements containing provisions that might be implicated by any divestiture of GRAIL or the EC Divestment Decision, including our ability to fully realize the anticipated economic benefits of our commercial arrangements with GRAIL and our obligations with respect to contingent value rights (the CVRs) issued by us in connection with the GRAIL acquisition and the risk that we will be unable to fully discharge such obligations in connection with a divestiture of GRAIL, that a divestiture will result in a change in obligor on the CVRs and/or of other consequences related thereto, which may adversely affect us and our business and/or the market value of the CVRs;
the risk of adverse effects resulting from additional potential litigation associated with the acquisition of GRAIL, such as additional legal, financial advisory, regulatory and other professional services fees;
the risk of additional litigation arising against us in connection with the GRAIL acquisition;
the assumptions underlying our critical accounting policies and estimates;
our assessments and estimates that determine our effective tax rate;
our assessments and beliefs regarding the outcome of pending legal proceedings and any liability that we may incur as a result of those proceedings as well as the cost and potential diversion of management resources associated with these proceedings;
uncertainty, or adverse economic and business conditions, including as a result of slowing or uncertain economic growth, COVID-19 pandemic mitigation measures, or armed conflict; and
other factors detailed in our filings with the Securities and Exchange Commission (SEC), including the risks, uncertainties, and assumptions described in “Risk Factors” within the Business & Market Information section of our Annual Report on Form 10-K for the fiscal year ended January 1, 2023, the “Other Key Information” section of our Quarterly Report on Form 10-Q for the period ended April 2, 2023
4

and on Form 10-Q for the period ended July 2, 2023, the “Risk Factors” section below, or in information disclosed in public conference calls, the date and time of which are released beforehand.
Any forward-looking statement made by us in this Quarterly Report on Form 10-Q is based only on information currently available to us and speaks only as of the date on which it is made. We undertake no obligation, and do not intend, to publicly update any forward-looking statement, whether written or oral, that may be made from time to time, or to review or confirm analysts’ expectations, or to provide interim reports or updates on the progress of any current financial quarter, in each case whether as a result of new information, future developments, or otherwise.
5

CONDENSED CONSOLIDATED FINANCIAL STATEMENTS

ILLUMINA, INC.
CONDENSED CONSOLIDATED BALANCE SHEETS
(In millions)
October 1,
2023
January 1,
2023
 (Unaudited) 
ASSETS
Current assets:
Cash and cash equivalents$927 $2,011 
Short-term investments6 26 
Accounts receivable, net690 671 
Inventory, net615 568 
Prepaid expenses and other current assets268 285 
Total current assets2,506 3,561 
Property and equipment, net1,040 1,091 
Operating lease right-of-use assets581 653 
Goodwill2,527 3,239 
Intangible assets, net3,029 3,285 
Other assets439 423 
Total assets$10,122 $12,252 
LIABILITIES AND STOCKHOLDERS’ EQUITY
Current liabilities:
Accounts payable$240 $293 
Accrued liabilities1,242 1,232 
Term notes, current portion 500 
Convertible senior notes, current portion 748 
Total current liabilities1,482 2,773 
Operating lease liabilities698 744 
Term notes1,489 1,487 
Other long-term liabilities555 649 
Stockholders’ equity:
Common stock2 2 
Additional paid-in capital9,487 9,207 
Accumulated other comprehensive income21 3 
Retained earnings157 1,142 
Treasury stock, at cost(3,769)(3,755)
Total stockholders’ equity5,898 6,599 
Total liabilities and stockholders’ equity$10,122 $12,252 

See accompanying notes to condensed consolidated financial statements.

6

ILLUMINA, INC.
CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS
(Unaudited)
(In millions, except per share amounts)
 
 Three Months EndedNine Months Ended
 October 1,
2023
October 2,
2022
October 1,
2023
October 2,
2022
Revenue:
Product revenue$941 $963 $2,864 $3,039 
Service and other revenue178 152 518 462 
Total revenue1,119 1,115 3,382 3,501 
Cost of revenue:
Cost of product revenue293 280 884 866 
Cost of service and other revenue95 72 285 210 
Amortization of acquired intangible assets47 46 143 125 
Total cost of revenue435 398 1,312 1,201 
Gross profit684 717 2,070 2,300 
Operating expense:
Research and development315 325 1,013 975 
Selling, general and administrative303 146 1,127 865 
Goodwill and intangible impairment821 3,914 821 3,914 
Legal contingency and settlement(1)(11)14 598 
Total operating expense1,438 4,374 2,975 6,352 
Loss from operations(754)(3,657)(905)(4,052)
Other income (expense):
Interest income13 3 47 4 
Interest expense(19)(6)(59)(17)
Other expense, net(22)(12)(33)(103)
Total other expense, net(28)(15)(45)(116)
Loss before income taxes(782)(3,672)(950)(4,168)
(Benefit) provision for income taxes(28)144 36 97 
Net loss$(754)$(3,816)$(986)$(4,265)
Loss per share:
Basic$(4.77)$(24.26)$(6.23)$(27.13)
Diluted$(4.77)$(24.26)$(6.23)$(27.13)
Shares used in computing loss per share:
Basic 158 157 158 157 
Diluted158 157 158 157 
See accompanying notes to condensed consolidated financial statements.

7

ILLUMINA, INC.
CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE LOSS
(Unaudited)
(In millions)
 
 Three Months EndedNine Months Ended
 October 1,
2023
October 2,
2022
October 1,
2023
October 2,
2022
Net loss$(754)$(3,816)$(986)$(4,265)
Unrealized gain on cash flow hedges, net of deferred tax9 9 18 22 
Total comprehensive loss$(745)$(3,807)$(968)$(4,243)

See accompanying notes to condensed consolidated financial statements.

8

ILLUMINA, INC.
CONDENSED CONSOLIDATED STATEMENTS OF STOCKHOLDERS’ EQUITY
(Unaudited)
(In millions)
AdditionalAccumulated OtherTotal
 Common StockPaid-InComprehensiveRetainedTreasury StockStockholders’
 SharesAmountCapitalIncomeEarningsSharesAmountEquity
Balance as of January 2, 2022197 $2 $8,938 $17 $5,485 (40)$(3,702)$10,740 
Net income— — — — 86 — — 86 
Unrealized gain on cash flow hedges, net of deferred tax— — — 1 — — — 1 
Issuance of common stock, net of repurchases— — 33 — — — (12)21 
Share-based compensation— — 79 — — — — 79 
Cumulative-effect adjustment from adoption of ASU 2020-06, net of deferred tax— — (93)— 61 — — (32)
Balance as of April 3, 2022197 2 8,957 18 5,632 (40)(3,714)10,895 
Net loss— — — — (535)— — (535)
Unrealized gain on cash flow hedges, net of deferred tax— — — 12 — — — 12 
Issuance of common stock, net of repurchases— — — — — — (4)(4)
Share-based compensation— — 76 — — — — 76 
Balance as of July 3, 2022197 2 9,033 30 5,097 (40)(3,718)10,444 
Net loss— — — — (3,816)— — (3,816)
Unrealized gain on cash flow hedges, net of deferred tax— — — 9 — — — 9 
Issuance of common stock, net of repurchases— — 30 — — — (2)28 
Share-based compensation— — 66 — — — — 66 
Balance as of October 2, 2022197 2 9,129 39 1,281 (40)(3,720)6,731 
Net loss— — — — (139)— — (139)
Unrealized loss on cash flow hedges, net of deferred tax— — — (36)— — — (36)
Issuance of common stock, net of repurchases1 — — — — — (35)(35)
Share-based compensation— — 78 — — — — 78 
Balance as of January 1, 2023198 $2 $9,207 $3 $1,142 (40)$(3,755)$6,599 

See accompanying notes to condensed consolidated financial statements.









9

ILLUMINA, INC.
CONDENSED CONSOLIDATED STATEMENTS OF STOCKHOLDERS’ EQUITY
(Unaudited)
(In millions)
AdditionalAccumulated OtherTotal
 Common StockPaid-InComprehensiveRetainedTreasury StockStockholders’
 SharesAmountCapitalIncome (Loss)EarningsSharesAmountEquity
Balance as of January 1, 2023198 $2 $9,207 $3 $1,142 (40)$(3,755)$6,599 
Net income    3   3 
Unrealized loss on cash flow hedges, net of deferred tax   (4)   (4)
Issuance of common stock, net of repurchases  37    (9)28 
Share-based compensation  67     67 
Balance as of April 2, 2023198 2 9,311 (1)1,145 (40)(3,764)6,693 
Net loss    (234)  (234)
Unrealized gain on cash flow hedges, net of deferred tax   13    13 
Issuance of common stock, net of repurchases      (3)(3)
Share-based compensation  77     77 
Reclassification of liability-classified awards  9     9 
Balance as of July 2, 2023198 2 9,397 12 911 (40)(3,767)6,555 
Net loss    (754)  (754)
Unrealized gain on cash flow hedges, net of deferred tax   9    9 
Issuance of common stock, net of repurchases  30    (2)28 
Share-based compensation  60     60 
Balance as of October 1, 2023198 $2 $9,487 $21 $157 (40)$(3,769)$5,898 

See accompanying notes to condensed consolidated financial statements.
10

ILLUMINA, INC.
CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS
(Unaudited)
(In millions)
 Nine Months Ended
 October 1,
2023
October 2,
2022
Cash flows from operating activities:
Net loss$(986)$(4,265)
Adjustments to reconcile net loss to net cash provided by operating activities:
Depreciation expense175 158 
Amortization of intangible assets148 130 
Share-based compensation expense286 266 
Deferred income taxes(42)(40)
Goodwill and intangible (IPR&D) impairment
821 3,914 
Property and equipment and right-of-use asset impairment
56  
Net losses on strategic investments39 79 
(Gain) loss on Helix contingent value right(8)8 
Payment of accreted debt discount(15) 
Change in fair value of contingent consideration liabilities(82)(230)
Unrealized loss on foreign exchange translation
21 1 
Other9 6 
Changes in operating assets and liabilities:
Accounts receivable(31)13 
Inventory(47)(127)
Prepaid expenses and other current assets(3)10 
Operating lease right-of-use assets and liabilities, net(13)(10)
Other assets6 17 
Accounts payable(50)(51)
Accrued liabilities(25)388 
Other long-term liabilities(5)(22)
Net cash provided by operating activities254 245 
Cash flows from investing activities:
Purchases of property and equipment(144)(198)
Purchases of strategic investments(19)(26)
Sales of strategic investments18  
Net cash paid for acquisitions (85)
Cash paid for intangible asset(1)(180)
Net cash used in investing activities(146)(489)
Cash flows from financing activities:
Debt issuance costs paid for credit facility(1) 
Payments on financing obligations
(1,235) 
Taxes paid related to net share settlement of equity awards(14)(19)
Proceeds from issuance of common stock67 63 
Net cash (used in) provided by financing activities(1,183)44 
Effect of exchange rate changes on cash and cash equivalents(9)(32)
Net decrease in cash and cash equivalents(1,084)(232)
Cash and cash equivalents at beginning of period2,011 1,232 
Cash and cash equivalents at end of period$927 $1,000 
    

See accompanying notes to condensed consolidated financial statements.
11

ILLUMINA, INC.
NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS
(UNAUDITED)
Unless the context requires otherwise, references in this report toIllumina,” the “Company,” “we,” “us,” and “our” refer to Illumina, Inc. and its consolidated subsidiaries.
1. ORGANIZATION AND SIGNIFICANT ACCOUNTING POLICIES
Business Overview
We are a provider of sequencing- and array-based solutions, serving customers in the research, clinical and applied markets. Our products are used for applications in the life sciences, oncology, reproductive health, agriculture and other emerging segments. Our customers include leading genomic research centers, academic institutions, government laboratories, and hospitals, as well as pharmaceutical, biotechnology, commercial molecular diagnostic laboratories, and consumer genomics companies.
On August 18, 2021, we acquired GRAIL, a healthcare company focused on early detection of multiple cancers. The acquisition is subject to ongoing legal proceedings and, currently, GRAIL must be held and operated separately and independently from Illumina pursuant to the transitional measures ordered by the European Commission in the EC Divestment Decision, following the prohibition of our acquisition of GRAIL on September 6, 2022. Refer to note “7. Legal Proceedings” for additional details. GRAIL is a separate reportable segment.
With respect to GRAIL, we have retained advisors and are preparing for sale and capital markets transaction options in accordance with the European Commission’s divestiture order. In parallel, ongoing appeals preserve flexibility for any divestiture of GRAIL and future transactions.
Basis of Presentation
The accompanying unaudited condensed consolidated financial statements have been prepared in accordance with U.S. generally accepted accounting principles (GAAP) for interim financial information and the instructions to Form 10-Q and Article 10 of Regulation S-X. Accordingly, they do not include all of the information and footnotes required by GAAP for complete financial statements. Interim financial results are not necessarily indicative of results anticipated for the full year. These unaudited condensed consolidated financial statements should be read in conjunction with the audited consolidated financial statements and footnotes included in the Annual Report on Form 10-K for the fiscal year ended January 1, 2023, from which the prior year balance sheet information herein was derived. The preparation of financial statements requires management to make estimates and assumptions that affect the reported amounts of assets, liabilities, revenue, and expense, and related disclosure of contingent assets and liabilities. Though the COVID-19 pandemic, the armed conflict between Russia and Ukraine, and macroeconomic factors such as inflation, exchange rates and concerns about an economic downturn present additional uncertainty, we continue to use the best information available to form our critical accounting estimates. Actual results could differ from those estimates.
The unaudited condensed consolidated financial statements include our accounts, our wholly-owned subsidiaries, and majority-owned or controlled companies. All intercompany transactions and balances have been eliminated in consolidation. Certain prior period amounts have been reclassified to conform to the current period presentation. In management’s opinion, the accompanying unaudited condensed consolidated financial statements reflect all adjustments, consisting of normal recurring adjustments, considered necessary for a fair presentation of the results for the interim periods presented.
Fiscal Year
Our fiscal year is the 52 or 53 weeks ending the Sunday closest to December 31, with quarters of 13 or 14 weeks ending the Sunday closest to March 31, June 30, September 30, and December 31. References to Q3 2023 and Q3 2022 refer to the three months ended October 1, 2023 and October 2, 2022, respectively, which were both 13 weeks, and references to year-to-date (YTD) 2023 and 2022 refer to the nine months ended October 1, 2023 and October 2, 2022, respectively, which were both 39 weeks.
12

Significant Accounting Policies
During YTD 2023, there were no changes to our significant accounting policies as described in our Annual Report on Form 10-K for the fiscal year ended January 1, 2023, with the exception of the following for income taxes:
Historically, we calculated the provision/(benefit) for income taxes for interim periods utilizing an estimated annual effective tax rate applied to the income/(loss) for the reporting period, except in Q2 2023 when a year-to-date effective tax rate method was utilized. We determined the estimated annual effective tax rate method would provide a more reliable estimate of the provision for income taxes for Q3 2023 and YTD 2023 since minor changes in the estimated income/(loss) before income taxes would not result in significant changes in the estimated annual effective tax rate.
Loss per Share
Basic loss per share is computed based on the weighted average number of common shares outstanding during the period. Diluted loss per share is computed based on the sum of the weighted average number of common shares and potentially dilutive common shares outstanding during the period. In loss periods, basic and diluted loss per share are identical since the effect of potentially dilutive common shares is antidilutive and therefore excluded.
Potentially dilutive common shares consist of shares issuable under convertible senior notes and equity awards. We utilize the if-converted method to calculate the impact of convertible senior notes on diluted loss per share. Potentially dilutive common shares from equity awards are determined using the average share price for each period under the treasury stock method. In addition, proceeds from exercise of equity awards and the average amount of unrecognized compensation expense for equity awards are assumed to be used to repurchase shares.
The following table presents the weighted average shares used to calculate basic and diluted loss per share:
In millionsQ3 2023Q3 2022YTD 2023YTD 2022
Weighted average shares used in calculating basic loss per share158 157 158